Park Royal estate is the largest industrial and business location in the UK. The estate services Heathrow and London markets, exports goods and services, and has access to the trunk road network for the whole of the UK.

As well as many small industrial firms, Park Royal is the location of some large company buildings, includingᅠMcVities,ᅠJohn LewisᅠandᅠKolak. The old Guinness brewery and sports ground site at the south-western extremity of the district has now been totally demolished andᅠSEGROᅠhas replaced this with its newᅠOriginᅠsite. The first building erected adjacent to the new roundabout and bridge link to Western Avenue is occupied by international drinks companyᅠDiageo, owner of the Guinness brand and the redevelopment site.